The latest report titled “Mannitol Production” by Procurement Resource, a global procurement research and consulting firm, provides an in-depth cost analysis of the production process of Mannitol.
Procurement Resource study is based on the latest prices and other economic data available. It also offers additional analysis of the report with detailed breakdown of all cost components (capital investment details, production cost details, economics for another plant location, dynamic cost model). In addition, the report incorporates the production process with detailed process and material flow, capital investment, operating costs along with financial expenses and depreciation charges.
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Procurement Resource’s detailed report describes the stepwise consumption of material and utilities along with a detailed process flow diagram. Furthermore, the study assesses the latest developments within the industry that might influence Mannitol production cost, looking into capacity expansions, plant turnarounds, mergers, acquisitions, and investments.
Procurement Resource Assessment of Mannitol Production Process:
- From Hydrogenation Reaction: This report presents the detailed production methodology and cost analysis of Mannitol industrial production across Mannitol manufacturing plants. The manufacturing process for mannitol, particularly d-mannitol, initiates with a chemical reaction involving d-fructose and d-glucose under specific conditions. This procedure uses an equal mix (50:50) of d-fructose and d-glucose, catalyzed by Raney nickel. The reaction takes place at a high temperature, between 120 and 160°C, and under significant pressure, roughly 70 to 140 atm. Through this method, the mixture undergoes hydrogenation, ultimately producing d-mannitol, commonly known as mannitol, as the end product.
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Product Definition:
Mannitol is a type of sugar alcohol used widely in the food, pharmaceutical, and medical industries due to its unique properties. It is derived from mannose by reduction and has a sweet taste, though it is less sweet than sucrose. Mannitol is notable for its ability to not be metabolized by oral bacteria, which means it does not contribute to tooth decay, making it a popular sweetener in chewing gums and toothpaste. In the pharmaceutical industry, mannitol serves multiple roles: as a diuretic to increase urine production, as an osmotic agent to reduce intracranial pressure or intraocular pressure, and as an excipient in the manufacture of chewable tablets and powders due to its pleasant taste and mouthfeel. Furthermore, mannitol's low glycemic index and non-insulin mediated absorption make it suitable for diabetic food products. Its ability to promote rehydration and electrolyte balance also makes it valuable in medical settings.
Market Drivers:
Market drivers for mannitol are largely influenced by its diverse applications across the pharmaceutical, food, and healthcare sectors. In pharmaceuticals, mannitol's role as a diuretic, osmotic agent, and excipient drives its demand for medical treatments and drug formulation, benefiting patients requiring intracranial pressure management and those with kidney conditions. The food industry's shift towards sugar substitutes that offer lower caloric content and do not contribute to tooth decay or affect blood sugar levels significantly boosts mannitol's appeal as a sweetener, especially in products aimed at diabetic individuals or those seeking healthier lifestyle choices. Additionally, its use in oral care products like toothpaste and chewing gums, owing to its non-cariogenic properties, further propels market growth. The increasing consumer awareness about health and wellness, alongside the pharmaceutical industry's expansion, particularly in developing countries, continues to fuel the demand for mannitol in various applications.
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