Tadalista is available for purchase for men with erectile dysfunction (ED) to assist improve sexual excitement and performance. The active component in this case is sildenafil citrate, which inhibits phosphodiesterase type 5. Tadalista should only be used up to 20 mg once day.
Tadalafil works by preventing the PDE5 enzyme from breaking down cyclic guanosine monophosphate (cGMP). During sexual stimulation, the penis releases nitric oxide, which raises cyclic guanosine monophosphate (cGMP). This, in turn, causes blood vessels to relax and increases blood flow to the penis. An erection is the result of this increased blood flow.